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Table 5 Antioxidant biomarkers in Rat’s kidneys of different groups

From: Use of Nigella sativa silver nanocomposite as an alternative therapy against thioacetamide nephrotoxicity

Groups

Parameters

SOD

(U/mg protein)

CAT

(U/mg protein)

GPx

(U/mg protein)

GR

(nmol/min/mg protein)

GST

(µmol/h/mg protein)

GSH

(mmol/mg protein)

 

Control

78.23 b ±2.37

85.67 b ±1.89

58.63 b ±1.82

11.65 b ±0.405

0.678 b ±0.021

2.48 b ±0.093

 

NSAE

92.37 a ±2.69

102.26a ± 2.85

70.20 a ±1.64

13.65 a ±0.501

0.809 a ±0.015

3.01 a ±0.068

 

NS-Ag-NC

95.17 a ±2.12

103.76a ± 2.70

72.31 a ±1.80

14.13 a ±0.458

0.828 a ±0.019

3.02 a ±0.101

 

TAA

36.65 e ±1.31

41.36 e ±1.58

30.34 e ±1.00

6.03 d ±0.136

0.348 e ±0.009

1.19 e ±0.027

 

NSAE + TAA

57.14 d ±2.19

62.27 d ±2.25

45.93 d ±1.36

9.08 c ±0.282

0.542 d ±0.014

1.91 d ±0.041

 

NS-Ag-NC

+ TAA

69.30 c ±2.36

73.07 c ±2.12

53.07 c ±1.25

9.91 c ±0.293

0.601c ± 0.012

2.22 c ±0.077

 
  1. Values are expressed as means ± SE; n = 7/group. Mean values within a column not sharing common superscript letters (a, b, c, d, e) were significantly different, (F = 101.7, P < 0.0001). Variations are compared as follows: NSAE, NS-Ag-NC, and TAA groups are opposed to the control group while NSAE + TAA and NS-Ag-NC + TAA groups are compared to the TAA group