Table 1 Characteristics of the subjects participating in the study by status
From: The potential impact of dietary choices on melanoma risk: an anti-inflammatory diet
All | ||||||
|---|---|---|---|---|---|---|
cases | controls | |||||
Characteristics, N. (%) | (Na=542) | (Na=273) | (Na=269) | Pvalueb | OR(95%CI) | Pvalue |
Sex | ||||||
males | 243 (44.8) | 126 (46.1) | 117 (43.5) | |||
females | 299 (55.2) | 147 (53.9) | 152 (56.5) | 0.534 | ||
Age, y | ||||||
mean (SD) | 52.8 (15.5) | 53.7 (15.3) | 51.9 (15.6) | |||
median (IQR) | 53.6 (40.1–65.3) | 54.1 (40.6–66.0) | 52.6 (39.3–64.6) | 0.205c | ||
Education (yr) | ||||||
< 8 | 105 (19.4) | 46 (16.9) | 59 (21.9) | 1 | ||
8–13 | 345 (63.8) | 166 (61.0) | 179 (66.5) | 1.43 (0.87–2.35) | 0.160 | |
> 13 | 91 (16.8) | 60 (22.1) | 31 (11.5) | 0.003 | 2.87 (1.52–5.40) | 0.001 |
Hair colour | ||||||
black/dark brown | 292 (53.9) | 113 (41.4) | 179 (66.5) | 1 | ||
light brown | 173 (31.9) | 105 (38.5) | 68 (25.3) | 2.62 (1.76–3.90) | < 0.0001 | |
fair/blond/red | 77 (14.2) | 55 (20.1) | 22 (8.2) | < 0.0001 | 4.31 (2.46–7.54) | < 0.0001 |
Skin photo-typed | ||||||
III-IV | 247 (45.7) | 92 (33.8) | 155 (57.8) | 1 | ||
I-II | 293 (54.3) | 180 (66.2) | 113 (42.2) | < 0.0001 | 2.80 (1.95–4.03) | < 0.0001 |
Skin colour | ||||||
dark | 155 (28.8) | 45 (16.5) | 110 (41.3) | 1 | ||
fair | 384 (71.2) | 228 (83.5) | 156 (58.7) | < 0.0001 | 3.79 (2.50–5.74) | < 0.0001 |
Presence of freckles | ||||||
No | 363 (69.5) | 150 (57.7) | 213 (81.3) | 1 | ||
Yes | 159 (30.5) | 110 (42.3) | 49 (18.7) | < 0.0001 | 3.52 (2.33–5.31) | < 0.0001 |
Common nevi (n) | ||||||
0–59 | 398 (73.4) | 164 (60.1) | 234 (87.0) | 1 | ||
≥ 60 | 144 (26.6) | 109 (39.9) | 35 (13.0) | < 0.0001 | 5.41 (3.42–8.54) | < 0.0001 |
Solar lentigines | ||||||
none/few/moderate | 157 (29.2) | 47 (17.4) | 110 (41.2) | 1 | ||
high | 380 (70.8) | 223 (82.6) | 157 (58.8) | < 0.0001 | 3.60 (2.33–5.55) | < 0.0001 |
Family history of skin cancer | ||||||
No | 516 (96.1) | 259 (95.6) | 257 (96.6) | 1 | ||
Yes | 21 (3.9) | 12 (4.4) | 9 (3.4) | 0.532 | 1.32 (0.54–3.25) | 0.539 |
Presence of chronic disease (excluding CVDs) | ||||||
No | 386 (71.2) | 197 (72.2) | 189 (70.3) | 1 | ||
Yes | 156 (28.8) | 76 (27.8) | 80 (29.7) | 0.625 | 0.93 (0.64–1.36) | 0.703 |
Presence of chronic disease (including CVDs) | ||||||
No | 365 (67.3) | 182 (66.7) | 183 (68.0) | 1 | ||
Yes | 177 (32.7) | 91 (33.3) | 86 (32.0) | 0.735 | 1.08 (0.75–1.56) | 0.673 |
-765 G > C genotypes | ||||||
-765GG | 184 (60.7) | 102 (61.8) | 82 (59.4) | 1 | ||
-765GC | 102 (33.7) | 55 (33.3) | 47 (34.1) | 0.89 (0.53–1.47) | 0.637 | |
-765CC | 17 (5.6) | 8 (4.9) | 9 (6.5) | 0.795 | 0.67 (0.24–1.89) | 0.445 |