Fig. 3

Fold-change of cardiac gene expression of sod1 (A), sod2 (B), gpx1 (C), fxr (D), shp (E), and stat3 (F) in TRF group compared to HFD group. The gene expression of sod1 and stat3 was found to be significantly downregulated in the TRF group (*p < 0.05). Other genes, such as sod2, gpx1, and fxr, were upregulated but not significantly (p > 0.05) except for shp (*p < 0.05). Values are expressed as the mean fold-change (FC) with standard error of the mean (SEM)